Current Research
International, national and homegrown research projects currently recruiting participants at Barts Health
Bespoke
Working with London's cyclists to make our roads safer
Study initiated and developed by the team at Barts Orthopaedics, working to build a better environment for cyclists in London.
Report cycling incidents or near misses at collideoscope.org.uk
Latella-2
Evaluation of the Latella Knee Implant System for Medial Osteoarthritis Pain Reduction
International study initiated and developed by the team at Barts Orthopaedics following on from our successful first-in-man trial.
Testing of a novel implant for the management of osteoarthritis
WOLLF
Wound management of Open Lower Limb Fractures
A trial developed at The University of Warwick Clinical Trials Unit to compare infection rates with standard dressings or negative pressure wound therapy
SWIFFT
Scaphoid Waist Internal Fixation for Fractures Trial
A trial developed at The University Leicester with York Clinical Trials Unit to compare surgical fixation with conservative management for scaphoid fractures
TRIO-Physio
Targeted physiotherapy to improve outcomes after TKR
A trial developed at The University of Edinburgh Clinical Trials Unit to investigate the effect of targetted physiotherapy for patients with an Oxford Knee Score of 26 or below at their six week post-operative appointment
NMES for Pelvic Fractures
NMES (neuromuscular electrical muscle stimulation) and pelvic fracture rehabilitation
Study initiated and developed by the team at Barts Orthopaedics to test the effect of NMES on patient rehabilitation following surgery to fix a fractured pelvis
GUST
Genetic markers of slipped capital femoral epiphysis: a pilot study
A pilot study initiated and developed by Barts Orthopaedics and Queen Mary University London to analyse genetics of SCFE patients of all ages
Health
RCT comparing total hip arthroplasty and hemi-arthroplasty
Coming soon...
PATH-2
RCT comparing PRP with placebo injection in adults with Achilles tendon rupture
Coming soon...
Research Strands
Our colleagues, collaborators and corporate partners
Institute of Bioengineering at QMUL
Manoj Ramachandran is Director of Clinical Strategy and Musculoskeletal Translational Research at the Institute of Bioengineering, School of Engineering & Materials Sciences, QMUL
Manoj provides clinical leadership, innovation experience, and a critical patient-leading perspective. His work focuses on developing strategies for musculoskeletal regeneration, medical devices, and digital medicine. Current grants include sources such as MRC and ARUK.
Cartilage and Bone Research
Collaboration with the William Harvey Research Institute, QMUL
We work with leading bone and cartilage scientists to explore the basic sciences of these tissues and to develop an Orthopaedic and Rheumatology Biobank (ORB) for strategies in stratified medicine. Current grants such as ARUK and NIHR.
Mobile Health
Developing apps that change healthcare
Recent projects have included novel ways of consenting patients to collect medical images for teaching, research and clinical purposes and developing apps for tracking symptoms and providing rehabilitation in orthopaedic surgery. We have worked successfully with cutting edge start-ups such as umotif and with in-house embedded app developers such as QApps.
Medical Devices
Working with med tech companies in patient-focussed innovation
We work closely with bright start-ups to deliver innovative med tech solutions for real-world clinical problems. Companies we work with or have worked with range from early stage start-ups, such as Cotera Inc and Andiamo, to those we have helped and supported through to exit, such as Pivot Medical Inc. We span the entire range of biodesign from ideation through prototyping and first-in-man studies to large scale multicentre trials.
Profiles
Meet our team!
Manoj Ramachandran
Director of Orthopaedic Research
Manoj is a Consultant Orthopaedic and Trauma Surgeon in paediatric and young adult orthopaedics and trauma at Barts Health, based at The Royal London and Barts and The London Children’s Hospitals. He is the Lead for Paediatric Orthopaedics and the Director of Informatics and Innovation for Surgery and Cancer. His clinical interests are in paediatric orthopaedics and trauma, especially of the lower limb, and the young adult hip and knee (including arthroscopy of the hip and knee, preservation and sports injuries). Manoj has built international research collaborations globally and is an Honorary Reader and Director of Clinical Strategy and Musculoskeletal Translational Research at the Institute of Bioengineering at QMUL.
Jamila Kassam
Lead Research Physiotherapist
Jamila qualified as a physiotherapist from UWE in Bristol before starting work as a physiotherapist at Charing Cross Hospital. Having completed a variety of rotations as a junior and senior physiotherapist, Jamila was awarded a scholarship by the Medical Research Council to complete a Research Master’s Degree at Imperial College London. Jamila joined the Orthopaedic Department in April 2013 in a new role as a research physiotherapist, working with Manoj to initially build a research infrastructure, and is now delivering and developing research studies.
Catherine Hilton
Research Physiotherapist
Catherine qualified as a physiotherapist at the University of Brighton and has worked in NHS Trusts across London since 2007. Catherine was successful in obtaining a fellowship with the NIHR and completed a Clinical Research Master's Degree at King's College London.
Having recently joined the team in May 2015, she is supporting NIHR portfolio studies and working with the Manoj and Jamila to expand our existing research activity.
Paul Lee
Consultant Orthopaedic Surgeon
Paul is a consultant orthopaedic surgeon at Barts Health NHS Trust. His main clinical interests are in hip and knee arthroplasty reconstruction (primary and revision), young adult hip preservation surgery (peri-acetabular osteotomy, arthroscopy), and the surgical management of peri-prosthetic joint infection. His research interests and peer review publications are focused in these areas. He had previously published in basic sciences involving metal ions associated with metal-on-metal bearing, lubricant surface tension properties associated with bearing surfaces and the effects of inert synthetic lubrication, growth factors and synthetic bone graft in animal models.
